Tissue Modeling & Drug Development Core

The Tissue Modeling and Drug Development Core (TMDDC) provides a growing archive of fixed and living tissues, DNA, and RNA for sequencing to support the CaRE2 mission. We are also developing a robust, well-annotated biorepository of tissue samples from a racially and ethnically diverse Florida and California patient population and make them available to the CaRE2 investigators.

Together, the TMDDC leaders provide an unusual combination of synergistic skills and experiences ranging from highly technical pathological and research procedures to clinical therapeutics and from basic science to translational research to products to reduce cancer burden.

Virtual Repository

More than 180,000 remnant specimens collected with informed consent and made available to anyone with appropriate IRB approval or materials transfer agreement.
  • Fresh-frozen tissue samples: Tumor and matching normal from same patient, same organ
  • Mirror-image FFPE blocks of fresh-frozen tissue samples
  • Corresponding blood/blood derivatives: Plasma, serum, buffy coat
  • Retrospective and prospective specimen procurement services

Request Tissue

To request samples, you will need to submit specific information including proof of IRB approval, specific aims, statistical analysis, and detailed specimen information drawn from the above inventories.

Contact Us

To request samples, you will need to submit specific information including proof of IRB approval, specific aims, statistical analysis, and detailed specimen information drawn from the above inventories.

Want to Join Us?

If you share our interest in reducing cancer health disparities, please consider becoming a member of the CaRE² center. Investigators, trainees, community leaders, and advocates are welcome.

Meet the Tissue Modeling Core Team

Hernan Flores-Rozas​

TISSUE | FAMU​

Bodour Salhia

TISSUE | USC

Paul Okunieff

TISSUE | UF

Kristianna M. Fredenburg

TISSUE | UF

Contact Us

Have questions about working with the TMDDC? We’d love to hear from you. Please include any specific tissue type needs to allows us to better answer your question.